1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-oxo-, 1,1-dimethylethyl ester
1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-oxo-, 1,1-dimethylethyl ester
CAS: 409341-03-3
Molecular Formula: C9H15NO4
1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-oxo-, 1,1-dimethylethyl ester - Names and Identifiers
1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-oxo-, 1,1-dimethylethyl ester - Physico-chemical Properties
| Molecular Formula | C9H15NO4 |
| Molar Mass | 201.22 |
| Storage Condition | 2-8°C |
1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-oxo-, 1,1-dimethylethyl ester - Introduction
4-hydroxy-2-oxo-, 1,1-dimethyleyl ester (4-hydroxy-2-oxo-, 1-dimethyleyl ester) is an organic compound commonly referred to as N-Boc-Oxypyroglutamate. Its chemical formula is C12H19NO6.
The compound has the following properties:
-Appearance: Colorless solid
-Melting point: about 80-85°C
-Solubility: Soluble in some polar organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM).
N-Boc-Oxypyroglutamate are mainly used in the field of organic synthesis, specific uses include:
-As a synthetic drug intermediate: The compound can be used to prepare various drugs, especially neuropeptide drugs.
-As an amino acid protecting group: The N-Boc(tert-butyloxycarbonyl) group can be used to protect the carboxyl group of the amino acid to avoid unnecessary reactions in organic synthesis.
The preparation method of N-Boc-Oxypyroglutamate usually involves the following steps:
1. 1-Pyrrolidinecarbonyl chloride (1-Pyrrolidinecarbonyl chloride) is obtained by reacting 1-pyrrolidine carboxylic acid (1-pyridinecarbonyl).
2. react 1-pyrrolidine chloride with 4-hydroxy -2-oxoproline in the presence of sodium carbonate to generate N-Boc-Oxypyroglutamate.
For safety information, please note the following:
-When handling this compound, take appropriate personal protective measures, such as wearing protective glasses, protective gloves and laboratory coats.
-Avoid inhaling the dust or vapor of the compound and ensure that it is operated under well-ventilated conditions.
-In case of ingestion or skin contact, seek medical help immediately and provide information about the compound to your doctor.
The compound has the following properties:
-Appearance: Colorless solid
-Melting point: about 80-85°C
-Solubility: Soluble in some polar organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM).
N-Boc-Oxypyroglutamate are mainly used in the field of organic synthesis, specific uses include:
-As a synthetic drug intermediate: The compound can be used to prepare various drugs, especially neuropeptide drugs.
-As an amino acid protecting group: The N-Boc(tert-butyloxycarbonyl) group can be used to protect the carboxyl group of the amino acid to avoid unnecessary reactions in organic synthesis.
The preparation method of N-Boc-Oxypyroglutamate usually involves the following steps:
1. 1-Pyrrolidinecarbonyl chloride (1-Pyrrolidinecarbonyl chloride) is obtained by reacting 1-pyrrolidine carboxylic acid (1-pyridinecarbonyl).
2. react 1-pyrrolidine chloride with 4-hydroxy -2-oxoproline in the presence of sodium carbonate to generate N-Boc-Oxypyroglutamate.
For safety information, please note the following:
-When handling this compound, take appropriate personal protective measures, such as wearing protective glasses, protective gloves and laboratory coats.
-Avoid inhaling the dust or vapor of the compound and ensure that it is operated under well-ventilated conditions.
-In case of ingestion or skin contact, seek medical help immediately and provide information about the compound to your doctor.
Last Update：2024-04-09 15:17:57
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Product Name: TERT-BUTYL 4-HYDROXY-2-OXOPYRROLIDINE-1-CARBOXYLATE Visit Supplier Webpage Request for quotation
CAS: 409341-03-3
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 409341-03-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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